AS CALIFORNIA'S FIRST regular overland transcontinental stage connection with St. Louis, this pioneering stage route ran along the Missouri Trail. The trail was the most southerly and only all-weather route to California. Built directly beside the immigrant trail, it figured prominently in the settlers' diaries as their first glimpse of the promised land, the first well watered valley to be encountered after crossing the great southwestern deserts. The historic setting has changed very little from the time of the great western migration and presents a rare opportunity to experience the past.

The adobe maintains a high degree of integrity including a great deal of its historic fabric including the original fireplace mantle, much woodwork and vigas (ceiling beams). The ranch house plays a leading role in the history of the American West. It represents Mexican and American culture contact during the Mexican Republic; the Frontier period of the westward migration; and the Gold Rush and the cattle ranching industry from 19th century Californio to 20th century to today.

Its importance as the southern immigrant overland trail and Butterfield Stage Station cannot be overstated and it is for this significance that it was designated as a National Historic Landmark in 1962.